Clinical & Lifestyle Benefits

Minimally Invasive

The VenaSeal™ closure system reduces discomfort and recovery time.1-4  Only one needle stick of numbing medicine is required during the procedure, and no compression stockings are required afterward.*

*Some patients may benefit from the use of compression stockings post-procedure.

Faster Recovery – Patient Comfort

The VenaSeal™ closure system is designed to allow rapid return to normal activities3

Demonstrated Results

The VenaSeal™ closure system is designed to reduce recovery time.  Many patients return to normal activity immediately after the procedure.  Your doctor can help you determine when you can return to normal activity.

VS_legs_side-by-sideIndividual Results May Vary

Potential Risks

The VenaSeal™ closure system is minimally invasive and catheter-based. As such, it may involve the following risks. Your doctor can help you understand these risks.

•Allergic reaction to the VenaSeal™ adhesive
•Arteriovenous fistula (i.e., an abnormal connection between an artery and a vein)
•Bleeding from the access site
•Deep vein thrombosis (i.e., blood clot in the deep vein system)
•Edema (i.e., swelling) in the treated leg
•Hematoma (i.e., the collection of blood outside of a vessel)
•Hyperpigmentation (i.e., darkening of the skin)
•Infection at the access site
•Neurological deficits including stroke and death
•Non-specific mild inflammation of the cutaneous and subcutaneous tissue
•Paresthesia (i.e., a feeling of tingling, pricking, numbness or burning)
•Phlebitis (i.e., inflammation of a vein)
•Pulmonary embolism (i.e., blockage of an artery in the lungs)
•Urticaria (i.e., hives) or ulceration may occur at the site of injection
•Vascular rupture and perforation
•Visible scarring

To locate a vein specialist in your area, please visit our Find a Doctor Physician Locator.


1. Morrison, N. Use of Cyanoacrylate adhesive for Treatment of Incompetent Great Saphenous Veins: 12-month Results of the VeClose Trial, European Venous Forum, 2015.

2. Morrison N, Gibson K, McEnroe S, Goldman M, King T, Weiss R, Cher D, Jones A. Randomized trial comparing cyanoacrylate embolization and radio frequency ablation for incompetent great saphenous veins (VeClose). J Vasc Surg.

3. Almeida JI, Javier JJ, Mackay EG, Bautista C, Cher DJ, Proebstle TM. Two-year follow-up of first human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence. Phlebology / Venous Forum of the Royal Society of Medicine, 2014.

4. Proebstle TM, Alm J, Dimitri S et al. The European multicenter cohort study on cyanoacrylate embolization of refluxing great saphenous veins. J Vasc Surg Venous and Lymphat Disord.